Life Sciences: New life sciences study findings have been reported by researchers at Universitat Pompeu Fabra Scientists discuss in 'Central and peripheral consequences of the chronic blockade of CB1 cannabinoid receptor with rimonabant or taranabant' new findings in life sciences. "The endocannabinoid system plays a crucial role in the pathophysiology of obesity. However, the clinical use of cannabinoid antagonists has been recently stopped because of its central side-effects,"...
Enzyme Research: Researchers from Stowers Institute for Medical Research report recent findings in enzyme research A new study, 'Deacetylase inhibitors dissociate the histone-targeting ING2 subunit from the Sin3 complex,' is now available. According to recent research from the United States, "Histone deacetylase (HDAC) inhibitors are in clinical development for several diseases, including cancers and neurodegenerative disorders. HDACs 1 and 2 are among the targets of these inhibitors and are...
HIV/AIDS Genetics: Data on HIV/AIDS genetics reported by A.L. Fiser and co-researchers Investigators publish new data in the report 'Pairwise comparison of isogenic HIV-1 viruses: R5 phenotype replicates more efficiently than X4 phenotype in primary CD4+ T cells expressing physiological levels of CXCR4.' "CCR5-using (R5) HIV-1 strains are present during the whole course of the infection in all subjects, whereas CXCR4-using (X4) HIV-1 strains appear only in the...